Rat Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14) Protein
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935106861
info@markelab.com
Precio
234€ (10 µg)
Protein TNFSF14
proveedor
Abbexareference
abx069555Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Rat Tumor Necrosis Factor Ligand Superfamily, Member 14 (TNFSF14) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Background
TNFSF14, also known as LIGHT (Lymphotoxin-like, exhibits inducible expression, competes with herpes simplex virus glycoprotein D for HVEM, a receptor expressed by T lymphocytes), is a member of the tumor necrosis factor (TNF) superfamily. This ligand is pivotal in immune response modulation and is highly expressed by activated T cells, NK (natural killer) cells, and certain myeloid cells. LIGHT interacts with several receptors, including HVEM (Herpes Virus Entry Mediator), LTβR (Lymphotoxin beta receptor), and DcR3 (Decoy receptor 3), each playing a distinct role in immune signaling pathways. LIGHT’s functions are diverse and are integral to immune cell proliferation, differentiation, survival, and inflammation, with its dysregulation linked to several immune and inflammatory diseases, as well as certain cancers.
Características del producto
category
Proteins and Peptides
origin
Rat
host
E. coli
immunogen target
Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14)
host
E. coli
conjugation
Unconjugated
form
Lyophilized Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 21.5 kDa Observed MW (SDS-PAGE): 21 kDa Concentration: Prior to lyophilization: 100 µg/ml Sequence Fragment: Arg58-Ile239 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl and 5% Trehalose.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
TNFSF14
dry ice
No
availability
Shipped within 5-12 working days.
alias
Tumor necrosis factor ligand superfamily member 14,LTg,CD258,HVEML,LIGHT,Herpes virus entry mediator ligand,Herpesvirus entry mediator ligand
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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