Rat Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14) Protein
234€ (10 µg)
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name
Rat Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx069555
tested applications
WB, SDS-PAGE
Description
Rat Tumor Necrosis Factor Ligand Superfamily, Member 14 (TNFSF14) is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14) |
| Host | E. coli |
| Origin | Rat |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 21.5 kDa Observed MW (SDS-PAGE): 21 kDa Concentration: Prior to lyophilization: 100 µg/ml Sequence Fragment: Arg58-Ile239 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl and 5% Trehalose. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | M0RCN2 |
| Alias | Tumor necrosis factor ligand superfamily member 14,LTg,CD258,HVEML,LIGHT,Herpes virus entry mediator ligand,Herpesvirus entry mediator ligand |
| Background | Protein TNFSF14 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
TNFSF14, also known as LIGHT (Lymphotoxin-like, exhibits inducible expression, competes with herpes simplex virus glycoprotein D for HVEM, a receptor expressed by T lymphocytes), is a member of the tumor necrosis factor (TNF) superfamily. This ligand is pivotal in immune response modulation and is highly expressed by activated T cells, NK (natural killer) cells, and certain myeloid cells. LIGHT interacts with several receptors, including HVEM (Herpes Virus Entry Mediator), LTβR (Lymphotoxin beta receptor), and DcR3 (Decoy receptor 3), each playing a distinct role in immune signaling pathways. LIGHT’s functions are diverse and are integral to immune cell proliferation, differentiation, survival, and inflammation, with its dysregulation linked to several immune and inflammatory diseases, as well as certain cancers.
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