Mouse Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14) Protein

Este producto es parte de TNFSF14 - TNF superfamily member 14
Mouse Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein TNFSF14

proveedor

Abbexa

reference

abx069553

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Tumor Necrosis Factor Ligand Superfamily, Member 14 (TNFSF14) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

TNFSF14, also known as LIGHT (Lymphotoxin-like, exhibits inducible expression, competes with herpes simplex virus glycoprotein D for HVEM, a receptor expressed by T lymphocytes), is a member of the tumor necrosis factor (TNF) superfamily. This ligand is pivotal in immune response modulation and is highly expressed by activated T cells, NK (natural killer) cells, and certain myeloid cells. LIGHT interacts with several receptors, including HVEM (Herpes Virus Entry Mediator), LTβR (Lymphotoxin beta receptor), and DcR3 (Decoy receptor 3), each playing a distinct role in immune signaling pathways. LIGHT’s functions are diverse and are integral to immune cell proliferation, differentiation, survival, and inflammation, with its dysregulation linked to several immune and inflammatory diseases, as well as certain cancers.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14)


host

E. coli


conjugation

Unconjugated


form

Lyophilized Reconstitute in ddH2O to a concentration of 0.1-0.3 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 27.5 kDa Observed MW (SDS-PAGE): 26 kDa Concentration: Prior to lyophilization: 300 µg/ml Sequence Fragment: Thr51-Val239 Tag: N-terminal His tag


expression

Recombinant


purity

> 90%


buffer

Prior to lyophilization: 100 mM NaHCO<sub>3</sub>, 500 mM NaCl, pH 8.3, containing 0.01% Sarcosyl and 5% Trehalose.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

TNFSF14


dry ice

No


availability

Shipped within 5-7 working days.


alias

Tumor necrosis factor ligand superfamily member 14,LTg,CD258,HVEML,LIGHT,Herpes virus entry mediator ligand,Herpesvirus entry mediator ligand


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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