Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14) Antibody

Este producto es parte de TNFSF14 - TNF superfamily member 14
Product Graph
195€ (20 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx126722
tested applications
ELISA, WB

Description

TNFSF14 Antibody is a Rabbit Polyclonal against TNFSF14.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
O43557
Gene ID
8740
NCBI Accession
NP_003798.2
OMIM
604520
Alias
Tumor necrosis factor ligand superfamily member 14,LTg,CD258,HVEML,LIGHT,Herpes virus entry mediator ligand,Herpesvirus entry mediator ligand
Background
Antibody anti-TNFSF14
Status
RUO
Note
Concentration: 0.52 mg/ml - 

Descripción

TNFSF14, also known as LIGHT (Lymphotoxin-like, exhibits inducible expression, competes with herpes simplex virus glycoprotein D for HVEM, a receptor expressed by T lymphocytes), is a member of the tumor necrosis factor (TNF) superfamily. This ligand is pivotal in immune response modulation and is highly expressed by activated T cells, NK (natural killer) cells, and certain myeloid cells. LIGHT interacts with several receptors, including HVEM (Herpes Virus Entry Mediator), LTβR (Lymphotoxin beta receptor), and DcR3 (Decoy receptor 3), each playing a distinct role in immune signaling pathways. LIGHT’s functions are diverse and are integral to immune cell proliferation, differentiation, survival, and inflammation, with its dysregulation linked to several immune and inflammatory diseases, as well as certain cancers.

Related Products

EH0316

Human TNFSF14/LIGHT (Tumor necrosis factor ligand superfamily member 14) ELISA Kit

Ver Producto
FNab08830

TNFSF14 antibody

Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.

Ver Producto
P10084

Recombinant Mouse TNFSF14

Ver Producto