935106861
info@markelab.com
Precio
262.5€ (100 µl)
Polyclonal Antibody to Tumor Necrosis Factor Ligand Superfamily, Member 14 (TNFSF14).
TNFSF14, also known as LIGHT (Lymphotoxin-like, exhibits inducible expression, competes with herpes simplex virus glycoprotein D for HVEM, a receptor expressed by T lymphocytes), is a member of the tumor necrosis factor (TNF) superfamily. This ligand is pivotal in immune response modulation and is highly expressed by activated T cells, NK (natural killer) cells, and certain myeloid cells. LIGHT interacts with several receptors, including HVEM (Herpes Virus Entry Mediator), LTβR (Lymphotoxin beta receptor), and DcR3 (Decoy receptor 3), each playing a distinct role in immune signaling pathways. LIGHT’s functions are diverse and are integral to immune cell proliferation, differentiation, survival, and inflammation, with its dysregulation linked to several immune and inflammatory diseases, as well as certain cancers.
Primary Antibodies
Polyclonal
Mouse
Tumor Necrosis Factor Ligand Superfamily Member 14 / LIGHT (TNFSF14)
Rabbit
Unconjugated
Liquid
WB, IHC, IF/ICC
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
100 µl
200 µl
1 ml
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
TNFSF14
No
Shipped within 5-7 working days.
Tumor necrosis factor ligand superfamily member 14,LTg,CD258,HVEML,LIGHT,Herpes virus entry mediator ligand,Herpesvirus entry mediator ligand
This product is for research use only.
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