TSPY1 / TSPY3 Antibody
260€ (50 µl)
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935106861
info@markelab.com
name
TSPY1 / TSPY3 Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx210310
tested applications
ELISA, IHC
Description
TSPY1/TSPY3 Antibody is a Rabbit Polyclonal against TSPY1/TSPY3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | TSPY1/TSPY3 |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/2000 - 1/10000, IHC: 1/30 - 1/150. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q01534, P0CV98 |
| Alias | CT78,TSPY,DYS14,Pja923,Cancer/testis antigen 78,Testis-specific Y-encoded protein 5 |
| Background | Antibody anti-TSPY1 |
| Status | RUO |
Descripción
Testis specific protein Y-linked 1 (TSPY1) is a protein encoded by the TSPY gene family, which is primarily expressed in the testis, where it is involved in regulating spermatogenesis and male fertility TSPY1 is localized on the Y chromosome and plays a role in germ cell development, particularly in regulating the proliferation and differentiation of male germ cells The exact function of TSPY1 is still under investigation, but it is believed to be involved in maintaining the stability of spermatogonial stem cells and facilitating their progression through the stages of spermatogenesis TSPY1’s expression is tightly regulated during development, and its dysregulation has been associated with infertility and testicular cancers, particularly germ cell tumors In these cases, abnormal TSPY1 expression can contribute to tumorigenesis by promoting uncontrolled cell division and survival of malignant germ cells
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