Testis-Specific Y-Encoded Protein 1 (TSPY) Antibody

292.5€ (80 µl)
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935106861
info@markelab.com
name
Testis-Specific Y-Encoded Protein 1 (TSPY) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx025031
tested applications
ELISA, WB, IHC
Description
TSPY may be involved in sperm differentiation and proliferation.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Testis-Specific Y-Encoded Protein 1 (TSPY) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified through a protein A column, followed by peptide affinity purification. |
Size 1 | 80 µl |
Size 2 | 400 µl |
Form | Liquid |
Tested Applications | ELISA, WB, IHC |
Buffer | PBS containing 0.09% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q01534 |
Alias | CT78,TSPY,DYS14,Pja923,Cancer/testis antigen 78,Testis-specific Y-encoded protein 1 |
Background | Antibody anti-TSPY1 |
Status | RUO |
Descripción
Testis specific protein Y-linked 1 (TSPY1) is a protein encoded by the TSPY gene family, which is primarily expressed in the testis, where it is involved in regulating spermatogenesis and male fertility TSPY1 is localized on the Y chromosome and plays a role in germ cell development, particularly in regulating the proliferation and differentiation of male germ cells The exact function of TSPY1 is still under investigation, but it is believed to be involved in maintaining the stability of spermatogonial stem cells and facilitating their progression through the stages of spermatogenesis TSPY1’s expression is tightly regulated during development, and its dysregulation has been associated with infertility and testicular cancers, particularly germ cell tumors In these cases, abnormal TSPY1 expression can contribute to tumorigenesis by promoting uncontrolled cell division and survival of malignant germ cells
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