TRAF Family Member-Associated NF-Kappa-B Activator (TANK) Antibody
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Description
TRAF Family Member-Associated NF-Kappa-B Activator (TANK) Antibody is a Rabbit polyclonal antibody for the detection of Human TRAF Family Member-Associated NF-Kappa-B Activator (TANK).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | TRAF Family Member-Associated NF-Kappa-B Activator (TANK) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q92844 |
| Gene ID | 10010 |
| NCBI Accession | NP_001186064.1 |
| Alias | TANK,I-TRAF, ITRAF, TRAF2, TRAF family member associated NFKB activator |
| Background | Antibody anti-TANK |
| Status | RUO |
Descripción
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TRAF Family Member-Associated NF-Kappa-B Activator (TANK) Antibody
TANK Antibody is a Rabbit Polyclonal antibody against TANK. The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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