Trace Amine Associated Receptor 2 (TAAR2) Antibody
292.5€ (80 µl)
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Name
Trace Amine Associated Receptor 2 (TAAR2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx034813
Tested Applications
ELISA, WB, IHC
Description
Orphan receptor.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Trace Amine Associated Receptor 2 (TAAR2) Immunogen: KLH-conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TAAR2. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 40.1 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9P1P5 |
| NCBI Accession | NP_001028252.1, NP_055441.2 |
| Alias | TAAR2,GPR58,taR-2,GPR58,G protein-coupled receptor 58,trace amine receptor 2,trace amine associated receptor 2 (gene/pseudogene) |
| Background | Antibody anti-TAAR2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
TAAR2 is another member of the trace amine-associated receptor family, closely related to TAAR1. It is activated by trace amines like phenylethylamine and other endogenous amines. TAAR2 is expressed in the brain, particularly in regions involved in olfaction, limbic functions, and mood regulation. Similar to TAAR1, TAAR2 couples to Gi proteins and modulates the release of neurotransmitters such as dopamine, serotonin, and norepinephrine, influencing neuronal activity and emotional states. While its exact physiological role is not as well characterized as TAAR1, TAAR2 is believed to play a role in the modulation of mood and sensory processing. It is involved in regulating behaviors associated with anxiety, arousal, and stress responses. Dysregulation of TAAR2 signaling is thought to be involved in neuropsychiatric disorders such as anxiety and depression, and it may contribute to the development of conditions like schizophrenia. Research into TAAR2 offers new potential avenues for the development of novel treatments for mood disorders and neuropsychiatric conditions.
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