Taste Receptor Type 2 Member 9 (TAS2R9) Antibody
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Description
This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Taste Receptor Type 2 Member 9 (TAS2R9) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NYW1 |
| Alias | TAS2R9,T2R9,taste receptoR type 2 member 9,TRB6 |
| Background | Antibody anti-TAS2R9 |
| Status | RUO |
Descripción
TAS2R9 is a bitter taste receptor that, like other members of the TAS2R family, plays a role in detecting potentially harmful substances through bitter taste perception. This receptor is involved in the sensing of specific bitter molecules and is activated when these compounds bind to TAS2R9 in the taste buds. The activation of TAS2R9 triggers a cascade of intracellular events that generate the sensation of bitterness, which helps protect the body from ingesting toxic substances commonly associated with bitter flavors. The genetic variations in TAS2R9 influence individual sensitivity to bitterness, which may lead to different reactions to foods that contain bitter compounds. TAS2R9 has been studied for its role in food aversions, dietary preferences, and in the context of understanding how bitter receptors contribute to the regulation of food intake. These findings could have implications for managing food-related behaviors and the development of functional foods that modify bitterness.
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