Taste Receptor Type 1 Member 1 (TAS1R1) Antibody
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Description
The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Taste Receptor Type 1 Member 1 (TAS1R1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q7RTX1 |
| Alias | TAS1R1,GPR70,T1R1,TR1,G protein-coupled receptor 70,taste receptor,GM148,GPR70,T1R1,TR1 |
| Background | Antibody anti-TAS1R1 |
| Status | RUO |
Descripción
TAS1R1 is a member of the type 1 taste receptor family, which is involved in the detection of specific taste stimuli. This receptor is primarily responsible for sensing umami, the taste associated with amino acids, particularly L-glutamate, which is commonly found in proteins and savory foods. TAS1R1 is expressed in taste receptor cells on the tongue and works together with other receptors, such as TAS1R3, to form a heterodimeric receptor complex that can detect umami flavors. When TAS1R1 is activated by its ligands, it activates intracellular signaling pathways that send signals to the brain, contributing to the sensation of taste. TAS1R1 is also involved in the regulation of food intake, as umami flavors are often associated with nutrient-rich foods. Dysregulation of TAS1R1 signaling has been linked to changes in food preference, dietary habits, and the regulation of appetite.
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