T7 Single-stranded DNA-binding protein gp2.5 Antibody

Este producto es parte de DYNLL - dynein light chain LC8-type 1
T7 Single-stranded DNA-binding protein gp2.5 Antibody
169€ (20 µg)

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Name
T7 Single-stranded DNA-binding protein gp2.5 Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx109421
Tested Applications
ELISA

Description

T7 Single-stranded DNA-binding protein gp2.5 Antibody is a Rabbit Polyclonal antibody against T7 Single-stranded DNA-binding protein gp2.5. Recombinant Enterobacteria Phage T7 Single-Stranded Dna-Binding Protein Gp25 Protein (1-232Aa) Single-Stranded Dna-Binding Protein That Eliminates Secondary Structure In Long Ssdna Formed On The Lagging Strand Of The Replication ForkStimulates Dna Polymerase Activity And Increases The Efficiency Of Rna Primer Synthesis By Interacting With The Dna Polymerase And The Helicase/Primase Protein Gp4Disrupts Loops, Hairpins And Other Secondary Structures Present On Ssdna To Reduce And Eliminate Pausing Of Viral Dna Polymerase At Specific Sites During Elongation.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: T7 Single-stranded DNA-binding protein gp2.5
Immunogen: Recombinant Enterobacteria phage T7 Single-stranded DNA-binding protein gp2.5 protein (1-232AA).
Host
Rabbit
Reactivity
Bacteria
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P03696
Gene ID
1261080
Alias
DLC1,DLC8,DNCL1,DNCLC1,LC8,LC8a,PIN,hdlc1,8 kDa dynein light chain
Background
Antibody anti-DYNLL1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

Dynein light chain 1, cytoplasmic (DYNLL1) is a protein that plays a critical role in the regulation of motor protein activity, particularly the dynein motor complex, which is involved in intracellular transport and cell division DYNLL1 functions as part of the dynein complex by binding to the dynein intermediate and heavy chains, facilitating the movement of cellular cargo along microtubules in the cytoplasm This process is essential for the transport of vesicles, organelles, and protein complexes within the cell, and for maintaining the proper positioning of mitotic spindles during cell division DYNLL1 also has a role in regulating the actin cytoskeleton and modulating various signaling pathways, including those involved in apoptosis and stress responses Dysregulation of DYNLL1 has been linked to neurodegenerative diseases, where defective cellular transport and organelle dysfunction contribute to neuronal damage It is also implicated in cancer, where its interaction with key signaling pathways can influence tumor cell migration and metastasis DYNLL1’s essential functions in intracellular trafficking and cellular signaling underscore its importance in maintaining normal cellular function and tissue homeostasis

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