Suppressor of Ty 16 Homolog (SUPT16H) Antibody
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Description
Suppressor Of Ty 16 Homolog (S. Cerevisiae) Antibody is a Rabbit Polyclonal antibody against Suppressor Of Ty 16 Homolog (S. Cerevisiae).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Suppressor of Ty 16 Homolog (SUPT16H) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y5B9 |
| Gene ID | 11198 |
| OMIM | 605012 |
| Background | Antibody anti-SUPT16H |
| Status | RUO |
Descripción
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Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2(casein kinase II).
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