Steroid Hormone Receptor ERR1 (ESRRA) Antibody
383.5€ (100 µl)
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935106861
info@markelab.com
name
Steroid Hormone Receptor ERR1 (ESRRA) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx224440
tested applications
ELISA, FCM
Description
ESRRA Antibody is a Mouse Monoclonal against ESRRA.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Steroid Hormone Receptor ERR1 (ESRRA) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Purified from ascites by Protein G chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, FCM |
| Buffer | PBS, containing 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P25440 |
| Gene ID | 6046 |
| OMIM | 601540 |
| Alias | ERR1,ERRa,ESRL1,NR3B1,ERRalpha,Steroid hormone receptor ERR1,Estrogen receptor-like 1,Nuclear receptor subfamily 3 group B member 1 |
| Background | Antibody anti-ESRRA |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Estrogen related receptor alpha (ESRRA) is a nuclear receptor that is involved in regulating energy metabolism, mitochondrial function, and cellular differentiation ESRRA, also known as ERRα, is activated in response to metabolic signals and plays a central role in regulating the expression of genes involved in oxidative metabolism, fatty acid oxidation, and glucose homeostasis It is highly expressed in tissues with high metabolic activity, such as the heart, liver, and muscle, where it helps maintain cellular energy balance by modulating mitochondrial biogenesis and function ESRRA is also important for maintaining normal brain function, bone homeostasis, and cardiovascular health Dysregulation of ESRRA has been linked to metabolic disorders such as obesity, type 2 diabetes, and cardiovascular diseases, as well as certain types of cancer where altered mitochondrial function and energy metabolism contribute to tumor growth ESRRA represents a potential target for therapies aimed at enhancing metabolic health and preventing diseases related to mitochondrial dysfunction
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