Squamous Cell Carcinoma Antigen Recognized By T-Cells 3 (SART3) Antibody
637€ (100 µl)
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Name
Squamous Cell Carcinoma Antigen Recognized By T-Cells 3 (SART3) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx115816
Tested Applications
ELISA, WB, IHC
Description
Squamous Cell Carcinoma Antigen Recognized By T Cells 3 Antibody is a Rabbit Polyclonal antibody against Squamous Cell Carcinoma Antigen Recognized By T Cells 3.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Squamous Cell Carcinoma Antigen Recognized By T-Cells 3 (SART3) Immunogen: Human SART3. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q15020 |
| Gene ID | 9733 |
| NCBI Accession | NP_055521.1, NM_014706.3 |
| OMIM | 611684 |
| Alias | DSAP1,P100,RP11-13G14,TIP110,p110,p110(nrb)Tat-interacting protein of 110 kDa |
| Background | Antibody anti-SART3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Spliceosome associated factor 3, U4/U6 recycling protein (SART3) is a multifunctional protein that plays a critical role in the recycling of U4/U6 snRNPs during spliceosome disassembly SART3 ensures the efficient reassembly of U4/U6 complexes, which are required for the next round of pre-mRNA splicing, maintaining the fidelity and efficiency of gene expression Beyond its role in splicing, SART3 interacts with RNA-binding proteins and participates in the regulation of alternative splicing, influencing proteomic diversity SART3 is also implicated in the regulation of telomerase activity and cellular senescence, linking its function to genome stability Dysregulation of SART3 has been associated with cancers and autoimmune diseases, where abnormal RNA splicing contributes to altered gene expression and disease progression Recent studies suggest that SART3 interacts with viral RNAs during infections, regulating host-pathogen interactions and immune responses Its role in RNA metabolism, spliceosome recycling, and genome integrity highlights its importance in maintaining cellular function and gene regulation pathways
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