Signaling Lymphocytic Activation Molecule Family, Member 7 (SLAMF7) Antibody
637€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Signaling Lymphocytic Activation Molecule Family, Member 7 (SLAMF7) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx115587
Tested Applications
ELISA, WB
Description
SLAMF7 Antibody is a Rabbit Polyclonal antibody against SLAMF7.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Signaling Lymphocytic Activation Molecule Family, Member 7 (SLAMF7) Immunogen: Human SLAMF7. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NQ25 |
| Gene ID | 57823 |
| NCBI Accession | NM_021181.4 |
| OMIM | 606625 |
| Alias | CD2 subset 1,19A,CS1,CD319,CRACC,CD2-like receptor-activating cytotoxic cells,Membrane protein FOAP-12 |
| Background | Antibody anti-SLAMF7 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
SLAMF7 (SLAM Family Member 7), also known as CS1 (CD2 subset 1) or CRACC (CD319), is a cell surface glycoprotein belonging to the Signaling Lymphocyte Activation Molecule (SLAM) family within the immunoglobulin superfamily. SLAMF7 is primarily expressed on the surface of immune cells, especially on natural killer (NK) cells, plasma cells, and certain T-cell subsets, as well as dendritic cells and monocytes. This receptor plays a key role in immune cell activation, adhesion, and signal transduction, significantly influencing immune responses. SLAMF7 is particularly relevant in the context of immune surveillance and tumor cell recognition, as it acts as a co-stimulatory molecule for NK cells, enhancing their cytotoxic function against abnormal cells. In the tumor microenvironment, SLAMF7 can either promote anti-tumor immunity or, in some cases, contribute to immune evasion mechanisms that facilitate cancer cell survival. Its expression in multiple myeloma, where it is typically highly expressed, has made it a target for immunotherapy. The development of monoclonal antibodies against SLAMF7, like elotuzumab, has underscored its significance in cancer therapy.
Productos relacionados
Signaling Lymphocytic Activation Molecule Family, Member 7 (SLAMF7) Antibody
SLAMF7 Antibody is a Rabbit Polyclonal antibody against SLAMF7.…
Ver producto Signaling Lymphocytic Activation Molecule Family, Member 7 (SLAMF7) Antibody
SLAMF7 Antibody is a Rabbit Polyclonal antibody against SLAMF7.…
Ver producto Signaling Lymphocytic Activation Molecule Family, Member 7 (SLAMF7) Antibody
Rabbit Polyclonal against the SLAMF7 protein.…
Ver producto