Sialic Acid Binding Ig Like Lectin 15 (SIGLEC15) Antibody

Este producto es parte de SIGLEC - sialic acid binding Ig like lectin
Product Graph
292.5€ (80 µl)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Sialic Acid Binding Ig Like Lectin 15 (SIGLEC15) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx026294
tested applications
ELISA, WB, IHC

Description

Binds sialylated glycoproteins.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Sialic Acid Binding Ig Like Lectin 15 (SIGLEC15)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified through a protein A column, followed by peptide affinity purification.
Size 1
80 µl
Size 2
400 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
PBS containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q6ZMC9
Alias
CD33L3,HsT1361,SIGLEC-15,CD33 antigen-like 3
Background
Antibody anti-SIGLEC15
Status
RUO

Descripción

SIGLEC15 is predominantly expressed on macrophages, dendritic cells, and osteoclasts. Unlike other Siglecs, SIGLEC15 shows specificity for modified sialic acids and is crucial for osteoclast development and bone resorption. It interacts with ligands on T cells to regulate immune responses, making it a potential target for cancer immunotherapy as it suppresses anti-tumor immunity. SIGLEC15 is highly expressed in the tumor microenvironment and has been associated with poor prognosis in certain cancers. Its roles extend to tissue remodeling and maintaining immune homeostasis in non-inflammatory conditions.
Related Products
abx026294
Sialic Acid Binding Ig Like Lectin 15 (SIGLEC15) Antibody
Binds sialylated glycoproteins.
Ver Producto
abx213264
Sialic Acid Binding Ig Like Lectin 15 (SIGLEC15) Antibody
SIGLEC15 Antibody is a Rabbit Polyclonal against SIGLEC15.
Ver Producto
abx308090
Sialic Acid Binding Ig Like Lectin 15 (SIGLEC15) Antibody (HRP)
SIGLEC15 Antibody (HRP) is a Rabbit Polyclonal against SIGLEC15 conjugated to HRP.
Ver Producto