Sialic Acid Binding Ig Like Lectin 14 (SIGLEC14) Antibody (Biotin)
403€ (200 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Sialic Acid Binding Ig Like Lectin 14 (SIGLEC14) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx272468
tested applications
WB, IHC, IF/ICC
Description
Sialic Acid Binding Ig Like Lectin 14 (SIGLEC14) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Sialic Acid Binding Ig Like Lectin 14 (SIGLEC14).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Sialic Acid Binding Ig Like Lectin 14 (SIGLEC14) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 200 µl |
| Size 2 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Siglec-14 |
| Background | Antibody anti-SIGLEC14 |
| Status | RUO |
Descripción
SIGLEC14 is a member of the Siglec family expressed on myeloid cells, including monocytes and neutrophils. It is paired with SIGLEC5, with which it shares high sequence similarity, forming an activating counterpart to the inhibitory SIGLEC5. SIGLEC14 binds to sialic acid-containing glycans on pathogens and self-tissues, triggering pro-inflammatory responses. This protein has been implicated in innate immune activation, particularly in recognizing bacterial infections. SIGLEC14 also plays a role in the modulation of immune responses, balancing activation and tolerance. Genetic variations in SIGLEC14 can result in a fusion with SIGLEC5, altering its expression and immune function.
Related Products
Sialic Acid Binding Ig Like Lectin 14 (SIGLEC14) Antibody
Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors.
Ver Producto
Human Sialic Acid Binding Ig Like Lectin 14 (SIGLEC14) Protein
Recombinant Sialic Acid Binding Ig Like Lectin 14 (SIGLEC14) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Ver Producto
Sialic Acid Binding Ig Like Lectin 14 (SIGLEC14) Antibody
Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 14 (SIGLEC14).
Ver Producto