Sialic Acid Binding Ig Like Lectin 11 (SIGLEC11) Antibody
260€ (50 µl)
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Name
Sialic Acid Binding Ig Like Lectin 11 (SIGLEC11) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx339381
Tested Applications
ELISA, IHC
Description
SIGLEC11 Antibody is a Rabbit Polyclonal against SIGLEC11.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Sialic Acid Binding Ig Like Lectin 11 (SIGLEC11) Immunogen: Synthetic peptide of human SIGLEC11. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/1000 - 1/2000, IHC: 1/25 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96RL6 |
| Gene ID | 114132 |
| Alias | Sialic acid-binding lectin 11,Siglec-11 |
| Background | Antibody anti-SIGLEC11 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
SIGLEC11 is expressed predominantly in microglial cells in the brain and interacts with sialylated structures on neurons. It is unique among Siglecs for its role in modulating neuroinflammatory responses and maintaining neuronal integrity. Evolutionary studies show its expansion in humans, suggesting specialized functions in brain immunity and neuroprotection.
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