Sialic Acid Binding Ig Like Lectin 11 (SIGLEC11) Antibody
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Description
SIGLEC11 Antibody is a Rabbit Polyclonal against SIGLEC11.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Sialic Acid Binding Ig Like Lectin 11 (SIGLEC11) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/1000 - 1/2000, IHC: 1/25 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96RL6 |
| Gene ID | 114132 |
| Alias | Sialic acid-binding lectin 11,Siglec-11 |
| Background | Antibody anti-SIGLEC11 |
| Status | RUO |
Descripción
SIGLEC11 is expressed predominantly in microglial cells in the brain and interacts with sialylated structures on neurons. It is unique among Siglecs for its role in modulating neuroinflammatory responses and maintaining neuronal integrity. Evolutionary studies show its expansion in humans, suggesting specialized functions in brain immunity and neuroprotection.
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Sialic Acid Binding Ig Like Lectin 11 (SIGLEC11) Antibody
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