Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10) Antibody
286€ (100 µl)
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935106861
info@markelab.com
name
Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx104186
tested applications
WB, IHC, IF/ICC
Description
Polyclonal Antibody to Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96LC7 |
| Alias | SLG2,PRO940,SIGLEC-10,Siglec-like protein 2 |
| Background | Antibody anti-SIGLEC10 |
| Status | RUO |
Descripción
SIGLEC10 is a transmembrane protein expressed on various immune cells, including B cells, macrophages, and dendritic cells. It recognizes sialic acid-containing ligands and is known for its inhibitory role in immune responses, mediated through immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic tail. SIGLEC10 is implicated in preventing excessive inflammation and maintaining immune tolerance.
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