Human Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10) Protein
221€ (10 µg)
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935106861
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name
Human Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx069062
tested applications
WB, SDS-PAGE
Description
Recombinant Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 20.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met571-Gln697 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96LC7 |
| Alias | SLG2,PRO940,SIGLEC-10,Siglec-like protein 2 |
| Background | Protein SIGLEC10 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
SIGLEC10 is a transmembrane protein expressed on various immune cells, including B cells, macrophages, and dendritic cells. It recognizes sialic acid-containing ligands and is known for its inhibitory role in immune responses, mediated through immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic tail. SIGLEC10 is implicated in preventing excessive inflammation and maintaining immune tolerance.
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