Human Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10) Protein

Este producto es parte de SIGLEC - sialic acid binding Ig like lectin
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221€ (10 µg)

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935106861
info@markelab.com
name
Human Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx069062
tested applications
WB, SDS-PAGE

Description

Recombinant Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Sialic Acid Binding Ig Like Lectin 10 (SIGLEC10)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 20.1 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Met571-Gln697
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-12 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q96LC7
Alias
SLG2,PRO940,SIGLEC-10,Siglec-like protein 2
Background
Protein SIGLEC10
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

SIGLEC10 is a transmembrane protein expressed on various immune cells, including B cells, macrophages, and dendritic cells. It recognizes sialic acid-containing ligands and is known for its inhibitory role in immune responses, mediated through immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in its cytoplasmic tail. SIGLEC10 is implicated in preventing excessive inflammation and maintaining immune tolerance.

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