Serpin B5 (SERPINB5) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
Serpin B5 (SERPINB5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx014060
tested applications
ELISA, WB
Description
Rabbit polyclonal antibody against Serpin B5 protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Serpin B5 (SERPINB5) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/20000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P36952 |
| Alias | PI5,maspin,Serpin B5,Peptidase inhibitor 5 |
| Background | Antibody anti-SERPINB5 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
SERPINB5, also known as maspin (mammary serine protease inhibitor), is a member of the serpin (serine protease inhibitor) superfamily. Unlike many other serpins that function as protease inhibitors, SERPINB5 is unique in that it does not inhibit protease activity. Discovered in the early 1990s, SERPINB5 has since been the subject of extensive research due to its involvement in various cellular processes and its implications in cancer biology. This protein is encoded by the SERPINB5 gene located on chromosome 18q21.3, a region that has been associated with several types of cancer, particularly breast cancer. SERPINB5 is primarily expressed in epithelial cells and has been implicated in processes such as cell adhesion, migration, and apoptosis.
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