Serpin B5 (SERPINB5) Antibody

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Description
SERPINB5 Antibody is a Rabbit Polyclonal against SERPINB5.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Serpin B5 (SERPINB5) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen Affinity Chromatography. |
Size 1 | 20 µl |
Size 2 | 50 µl |
Size 3 | 100 µl |
Size 4 | 200 µl |
Size 5 | 1 ml |
Form | Liquid |
Tested Applications | ELISA, WB, IHC |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P36952 |
Gene ID | 5268 |
NCBI Accession | NP_002630.2, NM_002639.4 |
OMIM | 154790 |
Alias | PI5,maspin,Serpin B5,Peptidase inhibitor 5 |
Background | Antibody anti-SERPINB5 |
Status | RUO |
Descripción
SERPINB5, also known as maspin (mammary serine protease inhibitor), is a member of the serpin (serine protease inhibitor) superfamily. Unlike many other serpins that function as protease inhibitors, SERPINB5 is unique in that it does not inhibit protease activity. Discovered in the early 1990s, SERPINB5 has since been the subject of extensive research due to its involvement in various cellular processes and its implications in cancer biology. This protein is encoded by the SERPINB5 gene located on chromosome 18q21.3, a region that has been associated with several types of cancer, particularly breast cancer. SERPINB5 is primarily expressed in epithelial cells and has been implicated in processes such as cell adhesion, migration, and apoptosis.
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