Semaphorin 3B (SEMA3B) Antibody
169€ (20 µl)
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935106861
info@markelab.com
name
Semaphorin 3B (SEMA3B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx320794
tested applications
ELISA, IHC
Description
SEMA3B Antibody is a Rabbit Polyclonal against SEMA3B.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Semaphorin 3B (SEMA3B) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13214 |
| Gene ID | 7869 |
| NCBI Accession | NP_001005914.1, NM_001005914.2, NP_001276989.1, NM_001290060.1 |
| OMIM | 601281 |
| Alias | SemA,SEMA5,SEMAA,semaV,LUCA-1,Sema A(V),Semaphorin-V,Semaphorin-3B |
| Background | Antibody anti-SEMA3B |
| Status | RUO |
Descripción
SEMA3B (Semaphorin 3B) is known for its tumor-suppressive properties, particularly in lung and breast cancers, where its expression is often downregulated. Acting through neuropilin and plexin receptors, SEMA3B influences apoptosis, cell proliferation, and migration. It has roles in embryonic development, where it contributes to organogenesis and angiogenesis by modulating vascular patterning. The loss or mutation of SEMA3B is implicated in cancer progression and metastasis, making it a significant focus for therapeutic interventions aiming to restore its tumor-suppressive functions.
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