Semaphorin 3B (SEMA3B) Antibody

Este producto es parte de SEMA3 - semaphorin 3
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169€ (20 µl)

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935106861
info@markelab.com
name
Semaphorin 3B (SEMA3B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx320794
tested applications
ELISA, IHC

Description

SEMA3B Antibody is a Rabbit Polyclonal against SEMA3B.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Semaphorin 3B (SEMA3B)
Host
Rabbit
Reactivity
Human
Recommended Dilution
IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
20 µl
Size 2
50 µl
Size 3
100 µl
Size 4
200 µl
Size 5
1 ml
Form
Liquid
Tested Applications
ELISA, IHC
Buffer
PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q13214
Gene ID
7869
NCBI Accession
NP_001005914.1, NM_001005914.2, NP_001276989.1, NM_001290060.1
OMIM
601281
Alias
SemA,SEMA5,SEMAA,semaV,LUCA-1,Sema A(V),Semaphorin-V,Semaphorin-3B
Background
Antibody anti-SEMA3B
Status
RUO

Descripción

SEMA3B (Semaphorin 3B) is known for its tumor-suppressive properties, particularly in lung and breast cancers, where its expression is often downregulated. Acting through neuropilin and plexin receptors, SEMA3B influences apoptosis, cell proliferation, and migration. It has roles in embryonic development, where it contributes to organogenesis and angiogenesis by modulating vascular patterning. The loss or mutation of SEMA3B is implicated in cancer progression and metastasis, making it a significant focus for therapeutic interventions aiming to restore its tumor-suppressive functions.

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