Human Semaphorin 3B (SEMA3B) Protein
247€ (10 µg)
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935106861
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name
Human Semaphorin 3B (SEMA3B) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx655028
tested applications
WB, SDS-PAGE
Description
Human Semaphorin 3B (SEMA3B) Protein is a Recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Semaphorin 3B (SEMA3B) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 23.5 kDa Observed MW: 25 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Pro573-Trp749 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | SemA,SEMA5,SEMAA,semaV,LUCA-1,Sema A(V),Semaphorin-V,Semaphorin-3B |
| Background | Protein SEMA3B |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
SEMA3B (Semaphorin 3B) is known for its tumor-suppressive properties, particularly in lung and breast cancers, where its expression is often downregulated. Acting through neuropilin and plexin receptors, SEMA3B influences apoptosis, cell proliferation, and migration. It has roles in embryonic development, where it contributes to organogenesis and angiogenesis by modulating vascular patterning. The loss or mutation of SEMA3B is implicated in cancer progression and metastasis, making it a significant focus for therapeutic interventions aiming to restore its tumor-suppressive functions.
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