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Human Semaphorin 3B (SEMA3B) Protein
proveedor
Abbexareference
abx655028Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Human Semaphorin 3B (SEMA3B) Protein is a Recombinant Human protein expressed in E. coli.
Background
Semaphorins constitute a large family of cell surface and secreted guidance molecules, categorized into eight classes due to their structural variations, They show a conserved sema domain in their N-terminal region. They primarily function as short-range inhibitory signals, particularly crucial in directing axons away from inappropriate areas, especially during neural system development. Plexins are the primary receptors for semaphorins, often working alongside neuropilins as co-receptors in receptor complexes. These molecules have various roles, and some classes of semaphorins (SEMA3,SEMA4,SEMA4,SEMA6 ,SEMA7)are found in vertebrates, contributing to processes like atherosclerosis by affecting endothelial function, leukocyte infiltration, monocyte-macrophage retention, platelet hyperreactivity, and neovascularization. SEMA3B serves as an inhibitor of axonal extension and has demonstrated its role as a tumor suppressor by promoting apoptosis. Different transcript variants are produced due to alternative splicing of this gene. It is known by various aliases, including SemA, SEMA5, SEMAA, semaV, and LUCA-1.
Características del producto
category
Proteins and Peptides
origin
Human
host
E. coli
immunogen target
Semaphorin 3B (SEMA3B)
host
E. coli
conjugation
Unconjugated
form
Lyophilized
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
expression
Recombinant
purity
> 90%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
SEMA3B
dry ice
No
availability
Shipped within 5-7 working days.
alias
SemA,SEMA5,SEMAA,semaV,LUCA-1,Sema A(V),Semaphorin-V,Semaphorin-3B
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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