Semaphorin 3B (SEMA3B) Antibody

Este producto es parte de SEMA3 - semaphorin 3
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195€ (20 µl)

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935106861
info@markelab.com
name
Semaphorin 3B (SEMA3B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx006412
tested applications
ELISA, WB

Description

SEMA3B Antibody is a Rabbit Polyclonal Antibody against SEMA3B.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetSemaphorin 3B (SEMA3B)
HostRabbit
ReactivityHuman, Mouse
Recommended DilutionELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified by affinity chromatography.
Size 120 µl
Size 2100 µl
Size 32 × 100 µl
FormLiquid
Tested ApplicationsELISA, WB
BufferPBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ13214
Gene ID7869
NCBI AccessionNP_001005914.1
AliasSemA,SEMA5,SEMAA,semaV,LUCA-1,Sema A(V),Semaphorin-V,Semaphorin-3B
BackgroundAntibody anti-SEMA3B
StatusRUO
NoteConcentration: > 0.2 mg/ml -

Descripción

SEMA3B (Semaphorin 3B) is known for its tumor-suppressive properties, particularly in lung and breast cancers, where its expression is often downregulated. Acting through neuropilin and plexin receptors, SEMA3B influences apoptosis, cell proliferation, and migration. It has roles in embryonic development, where it contributes to organogenesis and angiogenesis by modulating vascular patterning. The loss or mutation of SEMA3B is implicated in cancer progression and metastasis, making it a significant focus for therapeutic interventions aiming to restore its tumor-suppressive functions.
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