Semaphorin 3B (SEMA3B) Antibody
195€ (20 µl)
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Name
Semaphorin 3B (SEMA3B) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx006412
Tested Applications
ELISA, WB
Description
SEMA3B Antibody is a Rabbit Polyclonal Antibody against SEMA3B.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Semaphorin 3B (SEMA3B) Immunogen: Recombinant protein corresponding to SEMA3B. The exact sequence is proprietary. |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 83 kDa Observed MW: 83 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13214 |
| Gene ID | 7869 |
| NCBI Accession | NP_001005914.1 |
| Alias | SemA,SEMA5,SEMAA,semaV,LUCA-1,Sema A(V),Semaphorin-V,Semaphorin-3B |
| Background | Antibody anti-SEMA3B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
SEMA3B (Semaphorin 3B) is known for its tumor-suppressive properties, particularly in lung and breast cancers, where its expression is often downregulated. Acting through neuropilin and plexin receptors, SEMA3B influences apoptosis, cell proliferation, and migration. It has roles in embryonic development, where it contributes to organogenesis and angiogenesis by modulating vascular patterning. The loss or mutation of SEMA3B is implicated in cancer progression and metastasis, making it a significant focus for therapeutic interventions aiming to restore its tumor-suppressive functions.
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