Roundabout Homolog 2 (ROBO2) Antibody

Este producto es parte de ROBO - roundabout guidance receptor
Product Graph
169€ (20 µl)

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935106861
info@markelab.com
name
Roundabout Homolog 2 (ROBO2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx321270
tested applications
ELISA, IHC

Description

ROBO2 Antibody is a Rabbit Polyclonal against ROBO2.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetRoundabout Homolog 2 (ROBO2)
HostRabbit
ReactivityHuman
Recommended DilutionIHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationAntigen Affinity Chromatography.
Size 120 µl
Size 250 µl
Size 3100 µl
Size 4200 µl
Size 51 ml
FormLiquid
Tested ApplicationsELISA, IHC
BufferPBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ9HCK4
Gene ID6092
NCBI AccessionNM_002942.4
OMIM602431
AliasNORS,NYS8,SAX3,CPHD8,DUTT1,Deleted in U twenty twenty,H-Robo-1,Roundabout homolog 1
BackgroundAntibody anti-ROBO2
StatusRUO

Descripción

ROBO2 (Roundabout Guidance Receptor 2) shares structural and functional similarities with ROBO1, playing a complementary role in neural development and guidance. It ensures the proper wiring of axonal tracts and is crucial for midline crossing of axons in the central nervous system. Beyond neural functions, ROBO2 is involved in kidney morphogenesis and epithelial tissue organization. It participates in Slit-dependent signaling pathways, which regulate cellular adhesion and migration. Aberrations in ROBO2 expression or function have been linked to congenital kidney abnormalities and developmental disorders, further underscoring its critical role in maintaining developmental and tissue-specific integrity.
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