Roundabout Homolog 2 (ROBO2) Antibody
52€ (10 µg)
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935106861
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name
Roundabout Homolog 2 (ROBO2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx119130
tested applications
ELISA, IHC
Description
ROBO2 Antibody is a Rabbit Polyclonal antibody against ROBO2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Roundabout Homolog 2 (ROBO2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/40000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9HCK4 |
| Gene ID | 6092 |
| OMIM | 602431 |
| Alias | NORS,NYS8,SAX3,CPHD8,DUTT1,Deleted in U twenty twenty,H-Robo-1,Roundabout homolog 1 |
| Background | Antibody anti-ROBO2 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
ROBO2 (Roundabout Guidance Receptor 2) shares structural and functional similarities with ROBO1, playing a complementary role in neural development and guidance. It ensures the proper wiring of axonal tracts and is crucial for midline crossing of axons in the central nervous system. Beyond neural functions, ROBO2 is involved in kidney morphogenesis and epithelial tissue organization. It participates in Slit-dependent signaling pathways, which regulate cellular adhesion and migration. Aberrations in ROBO2 expression or function have been linked to congenital kidney abnormalities and developmental disorders, further underscoring its critical role in maintaining developmental and tissue-specific integrity.
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