Retinoid X Receptor Gamma (RXRG) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
Retinoid X Receptor Gamma (RXRG) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx013188
tested applications
WB, IHC, IF/ICC
Description
Rabbit polyclonal antibody against Retinoid X Receptor gamma protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Retinoid X Receptor Gamma (RXRG) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | Validated in IF. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P48443 |
| Alias | RXRC,NR2B3,RXRgamma,RXR-gamma,Retinoic acid receptor RXR-gamma,Retinoid X receptor gamma,Nuclear receptor subfamily 2 group B member 3 |
| Background | Antibody anti-RXRG |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Retinoid X receptor gamma (RXRG) is another retinoid X receptor involved in regulating gene expression and cellular processes in response to retinoids RXRG shares many of the functions of RXRA and RXRB but is particularly involved in regulating genes related to energy metabolism, cell differentiation, and inflammation RXRG plays a key role in the regulation of lipid metabolism, glucose homeostasis, and the response to oxidative stress It is expressed in tissues such as adipose tissue, skeletal muscle, and the liver, where it helps control the transcription of genes involved in fat storage and energy utilization RXRG is also involved in regulating immune function and inflammation, particularly in the context of autoimmune diseases and inflammatory disorders Dysregulation of RXRG is associated with metabolic diseases like obesity, diabetes, and fatty liver disease, as well as certain cancers Its involvement in immune regulation and metabolic pathways makes RXRG a critical factor in maintaining overall homeostasis RXRG represents a potential therapeutic target for treating metabolic and inflammatory diseases, as well as cancers, by modulating its role in lipid metabolism, inflammation, and cell differentiation
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