Retinoid X Receptor alpha Protein
234€ (10 µg)
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Name
Retinoid X Receptor alpha Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx260438
Tested Applications
SDS-PAGE
Description
RXRA is a recombinant protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | RXRA |
| Assay Type | Activity: Not tested |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| UniProt ID | P19793 |
| Alias | NR2B1,RXRalpha,RXR-alpha,Retinoic acid receptor RXR-alpha,Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha |
| Background | Protein RXRA |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Retinoid X receptor alpha (RXRA) is a nuclear receptor that plays a crucial role in regulating gene expression in response to retinoids, which are derived from vitamin A RXRA forms heterodimers with other nuclear receptors, such as the retinoic acid receptor (RAR) and peroxisome proliferator-activated receptors (PPARs), to regulate genes involved in processes such as cell differentiation, metabolism, and immune responses RXRA is involved in the regulation of lipid metabolism, glucose homeostasis, and cellular growth and differentiation It also plays a role in the development and maintenance of the central nervous system and immune system RXRA’s activity is essential for maintaining metabolic balance and preventing diseases like cancer, cardiovascular disease, and metabolic disorders, as it regulates critical pathways in cellular growth and lipid homeostasis Dysregulation of RXRA signaling has been linked to various cancers, including breast and prostate cancers, as well as metabolic diseases and disorders related to vitamin A deficiency RXRA is also a target for therapies aimed at controlling metabolic and inflammatory diseases
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