Retinoic Acid Receptor Gamma (RARG) Antibody (Biotin)
169€ (20 µg)
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Name
Retinoic Acid Receptor Gamma (RARG) Antibody (Biotin)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx337476
Tested Applications
ELISA
Description
RARG Antibody (Biotin) is a Rabbit Polyclonal against RARG.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Retinoic Acid Receptor Gamma (RARG) Immunogen: Recombinant Human Retinoic acid receptor gamma protein (13-87AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P13631 |
| Gene ID | 5916 |
| Alias | RARC,NR1B3,RARgamma,Nuclear receptor subfamily 1 group B member 3 |
| Background | Antibody anti-RARG |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Retinoic acid receptor gamma (RARG) is another nuclear receptor that responds to retinoic acid and regulates the expression of genes involved in cellular differentiation, metabolism, and apoptosis RARG forms a heterodimer with RXR and binds to specific RAREs to regulate gene transcription It is essential for the proper development of various tissues, including the brain, skin, and heart, and plays a role in regulating metabolism and immune function RARG is involved in the differentiation of cells in the central nervous system, influencing processes like neurogenesis and neuronal plasticity It also regulates the immune response, particularly in T-cell differentiation and the resolution of inflammation Dysregulation of RARG has been linked to various diseases, including cancers and autoimmune conditions, where altered retinoic acid signaling can lead to uncontrolled cell growth or immune system dysfunction Studies suggest that RARG could be a potential target for therapies aimed at modulating retinoic acid signaling to treat diseases such as cancer and inflammatory disorders
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