Human Retinoic Acid Receptor gamma (RARg) ELISA Kit

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Description
Human Retinoic Acid Receptor gamma (RARg) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Retinoic Acid Receptor gamma (RARg) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Retinoic Acid Receptor Gamma (RARg)
Documents del producto
Product specifications
Category | ELISA Kits |
Immunogen Target | Retinoic Acid Receptor gamma (RARg) |
Reactivity | Human |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich |
Test Range | 0.156 ng/ml - 10 ng/ml |
Sensitivity | < 0.07 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Size 2 | 5 × 96 tests |
Size 3 | 10 × 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Tissue homogenates and other biological fluids. |
Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
Alias | RARC,NR1B3,RARgamma,Nuclear receptor subfamily 1 group B member 3 |
Background | Elisa kits for RARG |
Status | RUO |
Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Retinoic acid receptor gamma (RARG) is another nuclear receptor that responds to retinoic acid and regulates the expression of genes involved in cellular differentiation, metabolism, and apoptosis RARG forms a heterodimer with RXR and binds to specific RAREs to regulate gene transcription It is essential for the proper development of various tissues, including the brain, skin, and heart, and plays a role in regulating metabolism and immune function RARG is involved in the differentiation of cells in the central nervous system, influencing processes like neurogenesis and neuronal plasticity It also regulates the immune response, particularly in T-cell differentiation and the resolution of inflammation Dysregulation of RARG has been linked to various diseases, including cancers and autoimmune conditions, where altered retinoic acid signaling can lead to uncontrolled cell growth or immune system dysfunction Studies suggest that RARG could be a potential target for therapies aimed at modulating retinoic acid signaling to treat diseases such as cancer and inflammatory disorders
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