Retinoic Acid Receptor, Gamma (RARG) Antibody
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Description
Retinoic Acid Receptor, Gamma Antibody is a Rabbit Polyclonal antibody against Retinoic Acid Receptor, Gamma.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Retinoic Acid Receptor, Gamma (RARG) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P13631 |
| Gene ID | 5916 |
| NCBI Accession | NP_000957.1, NM_000966.5 |
| OMIM | 180190 |
| Alias | RARC,NR1B3,RARgamma,Nuclear receptor subfamily 1 group B member 3 |
| Background | Antibody anti-RARG |
| Status | RUO |
Descripción
Retinoic acid receptor gamma (RARG) is another nuclear receptor that responds to retinoic acid and regulates the expression of genes involved in cellular differentiation, metabolism, and apoptosis RARG forms a heterodimer with RXR and binds to specific RAREs to regulate gene transcription It is essential for the proper development of various tissues, including the brain, skin, and heart, and plays a role in regulating metabolism and immune function RARG is involved in the differentiation of cells in the central nervous system, influencing processes like neurogenesis and neuronal plasticity It also regulates the immune response, particularly in T-cell differentiation and the resolution of inflammation Dysregulation of RARG has been linked to various diseases, including cancers and autoimmune conditions, where altered retinoic acid signaling can lead to uncontrolled cell growth or immune system dysfunction Studies suggest that RARG could be a potential target for therapies aimed at modulating retinoic acid signaling to treat diseases such as cancer and inflammatory disorders
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