Retinoblastoma Protein 1 Phospho-Ser811 (RB1 pS811) Antibody
208€ (20 µl)
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Name
Retinoblastoma Protein 1 Phospho-Ser811 (RB1 pS811) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx000161
Tested Applications
ELISA, WB
Description
RB1 (pS811) Antibody is a Rabbit Polyclonal antibody against RB1 (pS811). The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB1), bladder cancer, and osteogenic sarcoma.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Retinoblastoma Protein 1 Phospho-Ser811 (RB1 pS811) Immunogen: A synthetic phosphorylated peptide around S811 of human RB. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 106 kDa Observed MW: 106 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P06400 |
| Gene ID | 5925 |
| NCBI Accession | NP_000312.2 |
| Background | Antibody anti-RB1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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