RB1 (pS795) Antibody is a Rabbit Polyclonal antibody against RB1 (pS795). The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB1), bladder cancer, and osteogenic sarcoma.
Primary Antibodies
Polyclonal
Human, Mouse, Rat
Retinoblastoma Protein 1 Phospho-Ser795 (RB1 pS795)
Rabbit
Unconjugated
Liquid
WB, IHC
Purified by affinity chromatography.
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
20 µl
50 µl
100 µl
200 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
RB1
No
Shipped within 5-10 working days.
NP_000312.2
This product is for research use only.
Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated...
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Ver másKey regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated...
Precio a consultar
Ver másRB1 (pS795) Antibody is a Rabbit Polyclonal antibody against RB1 (pS795). The protein encoded by this gene is a negative...
200€ (20 µl)
Ver más