Relaxin Family Peptide/INSL5 Receptor 4 (RXFP4) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
Relaxin Family Peptide/INSL5 Receptor 4 (RXFP4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx324200
tested applications
ELISA, WB, IF/ICC
Description
RXFP4 Antibody is a Rabbit Polyclonal against RXFP4.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Relaxin Family Peptide/INSL5 Receptor 4 (RXFP4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000, WB: 1/500 - 1/2000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8TDU9 |
| Gene ID | 339403 |
| Alias | RXFP4,RLN3R2,GPCR142,INSL5 receptor,RXFPR4,G protein-coupled receptor 100,relaxin/insulin-like family peptide receptor 4,relaxin/insulin like family peptide receptor 4,GPR100 |
| Background | Antibody anti-RXFP4 |
| Status | RUO |
Descripción
RXFP4, also known as the INSL5 receptor, is a G protein-coupled receptor activated by insulin-like peptide 5 (INSL5), a peptide hormone that plays a role in regulating gastrointestinal function, reproductive physiology, and metabolism. RXFP4 primarily couples to Gs proteins, increasing cAMP levels, and activating pathways involved in smooth muscle relaxation and hormone secretion. It is expressed in the gastrointestinal tract, pancreas, and reproductive organs, where it regulates processes such as intestinal motility, glucose homeostasis, and reproductive function. INSL5 and RXFP4 signaling is involved in the regulation of feeding behavior and insulin secretion. Dysregulation of RXFP4 signaling has been linked to metabolic disorders, such as obesity and type 2 diabetes, and gastrointestinal conditions, including irritable bowel syndrome (IBS). RXFP4 antagonists and agonists are being investigated for their potential therapeutic applications in treating metabolic diseases and gastrointestinal disorders.
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Relaxin Family Peptide/INSL5 Receptor 4 (RXFP4) Antibody
RXFP4 Antibody is a Rabbit Polyclonal against RXFP4.
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RXFP4 Antibody is a Rabbit Polyclonal against RXFP4.
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