Regulator of Nonsense Transcripts 3A (UPF3A) Antibody
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Description
Upf3 Regulator Of Nonsense Transcripts Homolog A (Yeast) Antibody is a Rabbit Polyclonal antibody against Upf3 Regulator Of Nonsense Transcripts Homolog A (Yeast).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Regulator of Nonsense Transcripts 3A (UPF3A) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H1J1 |
| Gene ID | 65110 |
| NCBI Accession | NP_075387.1, NM_023011.3, NP_542418.1, NM_080687.2 |
| OMIM | 605530 |
| Background | Antibody anti-UPF3A |
| Status | RUO |
Descripción
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UPF3A antibody
Involved in nonsense-mediated decay(NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex(EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex(including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. However, UPF3A is shown to be only marginally active in NMD as compared to UPF3B. Binds spliced mRNA upstream of exon-exon junctions. In vitro, weakly stimulates translation.
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Regulator of Nonsense Transcripts 3A (UPF3A) Antibody
Upf3 Regulator Of Nonsense Transcripts Homolog A (Yeast) Antibody is a Rabbit Polyclonal antibody against Upf3 Regulator Of Nonsense Transcripts Homolog A (Yeast).
Ver Producto
Regulator of Nonsense Transcripts 3A (UPF3A) Antibody
UPF3A Antibody is a Rabbit Polyclonal against UPF3A.
Ver Producto