Regulator Of G Protein Signaling 7 (RGS7) Antibody
312€ (60 µl)
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935106861
info@markelab.com
name
Regulator Of G Protein Signaling 7 (RGS7) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx005154
tested applications
WB
Description
RGS7 Antibody is a Rabbit Polyclonal antibody against RGS7.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Regulator Of G Protein Signaling 7 (RGS7) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P49802 |
| Gene ID | 6000 |
| NCBI Accession | NP_002915.3 |
| Background | Antibody anti-RGS7 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:10521509, PubMed:10862767). The RGS7/GNB5 dimer enhances GNAO1 GTPase activity(PubMed:10521509). May play a role in synaptic vesicle exocytosis(PubMed:12659861). Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling(PubMed:15897264).
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