RGS7 antibody
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935106861
info@markelab.com
name
RGS7 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07273
tested applications
ELISA, WB, IHC
Description
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form(PubMed:10521509, PubMed:10862767). The RGS7/GNB5 dimer enhances GNAO1 GTPase activity(PubMed:10521509). May play a role in synaptic vesicle exocytosis(PubMed:12659861). Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling(PubMed:15897264).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | regulator of G-protein signaling 7 (RGS7) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 62 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P49802 |
| Gene ID | 6000 |
| Alias | Regulator of G-protein signaling 7 (RGS7),RGS7 |
| Background | Antibody anti-RGS7 |
| Status | RUO |
| Note | Mol. Weight 62 kDa |
Descripción
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