Recombinant Human MFAP3

Este producto es parte de MFAP - microfibril associated protein
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935106861
info@markelab.com
name
Recombinant Human MFAP3
category
Proteins and Peptides
provider
FineTest
reference
P5390
tested applications
Western Blot,ELISA

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Product specifications

CategoryProteins and Peptides
Immunogen Target19-147
HostE.Coli
OriginHuman
Observed MW14.1 kDa
ExpressionRecombinant
PurityGreater than 95% by SDS-PAGE gel analyses
PurificationHis tag
Size 150μg
Size 2200μg
Size 31mg
FormLyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4
Tested ApplicationsWestern Blot,ELISA
BufferReconstitute with Sterile distilled water
Availability3-4 weeks
Storage-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution
UniProt IDP55082
AliasMicrofibril-associated glycoprotein 3
BackgroundProteins MFAP3
StatusRUO
NoteThis product is for research use only.

Microfibril-Associated Protein 3 (MFAP3) is a member of the microfibril-associated protein (MFAP) family, which are integral components of the extracellular matrix (ECM) and are involved in the assembly and stabilization of microfibrils. These microfibrils are primarily composed of fibrillin and provide critical structural support to connective tissues. MFAP3 interacts with fibrillin-1 and other ECM components to contribute to tissue integrity and elasticity.  MFAP3 is characterized by regions rich in cysteine residues, which allow for the formation of disulfide bonds, crucial for stabilizing microfibril structure. MFAP3 is expressed in various tissues, particularly those with significant elastic properties, such as the lung, skin, vasculature, and ligaments. MFAP3 is believed to play a role in microfibril organization and elastogenesis—the process by which elastic fibers are formed and maintained. These fibers are essential for the elasticity and resilience of tissues subjected to repetitive mechanical stress.

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