Microfibril-Associated Glycoprotein 3 (MFAP3) Antibody

Este producto es parte de MFAP - microfibril associated protein
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357.5€ (100 µg)

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935106861
info@markelab.com
name
Microfibril-Associated Glycoprotein 3 (MFAP3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx036650
tested applications
ELISA, WB

Description

Rabbit Polyclonal against the MFAP3 protein.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetMicrofibril-Associated Glycoprotein 3 (MFAP3)
HostRabbit
ReactivityHuman
Recommended DilutionELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified by antigen affinity column chromatography.
Size 1100 µg
Size 21 mg
FormLyophilized
Tested ApplicationsELISA, WB
BufferPrior to lyophilization: 1% BSA and 0.02% NaN3.
AvailabilityShipped within 7-15 working days.
StorageStore at -20 °C. Avoid repeated freeze/thaw cycles.
Dry IceNo
AliasMicrofibril-associated glycoprotein 3
BackgroundAntibody anti-MFAP3
StatusRUO
NoteConcentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. -

Descripción

Microfibril-Associated Protein 3 (MFAP3) is a member of the microfibril-associated protein (MFAP) family, which are integral components of the extracellular matrix (ECM) and are involved in the assembly and stabilization of microfibrils. These microfibrils are primarily composed of fibrillin and provide critical structural support to connective tissues. MFAP3 interacts with fibrillin-1 and other ECM components to contribute to tissue integrity and elasticity.  MFAP3 is characterized by regions rich in cysteine residues, which allow for the formation of disulfide bonds, crucial for stabilizing microfibril structure. MFAP3 is expressed in various tissues, particularly those with significant elastic properties, such as the lung, skin, vasculature, and ligaments. MFAP3 is believed to play a role in microfibril organization and elastogenesis—the process by which elastic fibers are formed and maintained. These fibers are essential for the elasticity and resilience of tissues subjected to repetitive mechanical stress.

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