Recombinant Human IGSF11
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935106861
info@markelab.com
name
Recombinant Human IGSF11
category
Proteins and Peptides
provider
FineTest
reference
P2987
tested applications
Western Blot, ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | 24-241 |
| Host | E.Coli |
| Origin | Human |
| Observed MW | 43.7 kDa |
| Expression | Recombinant |
| Purity | Greater than 85% by SDS-PAGE gel analyses |
| Purification | IF2DI tag |
| Size 1 | 50μg |
| Size 2 | 200μg |
| Size 3 | 1mg |
| Form | Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose and 0.01% proclin, pH7.4 |
| Tested Applications | Western Blot, ELISA |
| Buffer | Reconstitute with Sterile distilled water |
| Availability | 7 days |
| Storage | -20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution |
| UniProt ID | Q5DX21 |
| Alias | CT119,VSIG3,BTIGSF,Igsf13,BT-IgSF,CXADRL1,V-set and immunoglobulin domain-containing protein ,Brain and testis-specific immunoglobulin superfamily protein |
| Background | Proteins IGSF11 |
| Status | RUO |
| Note | This product is for research use only. |
IGSF11 is a transmembrane adhesion molecule primarily expressed in the brain, where it is localized at excitatory synapses. It contains Ig-like domains that mediate homophilic and heterophilic interactions with other synaptic proteins, influencing synaptic organization and plasticity. IGSF11 is essential for the stabilization of AMPA receptors, which are critical for synaptic transmission and long-term potentiation (LTP). Dysregulation of IGSF11 has been implicated in neurodevelopmental disorders such as autism spectrum disorders (ASD) and schizophrenia. It also plays a role in tumor biology, where it modulates cancer cell adhesion and migration in certain cancers.
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