anti- IGSF11 antibody

Name: anti- IGSF11 antibody
Brand: FineTest
SKU: FNab04190
Availability: OnlineOnly

Este producto es parte de IGSF - immunoglobulin superfamily member

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-IGSF11

proveedor

FineTest

reference

FNab04190

Tested Applications

ELISA, WB, IHC

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth.

Background

IGSF11 is a transmembrane adhesion molecule primarily expressed in the brain, where it is localized at excitatory synapses. It contains Ig-like domains that mediate homophilic and heterophilic interactions with other synaptic proteins, influencing synaptic organization and plasticity. IGSF11 is essential for the stabilization of AMPA receptors, which are critical for synaptic transmission and long-term potentiation (LTP). Dysregulation of IGSF11 has been implicated in neurodevelopmental disorders such as autism spectrum disorders (ASD) and schizophrenia. It also plays a role in tumor biology, where it modulates cancer cell adhesion and migration in certain cancers.

Características del producto

clonality

polyclonal

reactivity

human,mouse,rat

immunogen target

immunoglobulin superfamily, member 11

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IHC

observerd MW

40-50kd

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

IGSF11

alias

CT119,VSIG3,BTIGSF,Igsf13,BT-IgSF,CXADRL1,V-set and immunoglobulin domain-containing protein ,Brain and testis-specific immunoglobulin superfamily protein

uniprot id

https://www.uniprot.org/uniprotkb/Q5DX21

gene id

https://www.ncbi.nlm.nih.gov/gene/152404

note

This product is for research use only.

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Human IGSF11(Immunoglobulin superfamily member 11) ELISA Kit

proveedor

FineTest

reference

EH9338

reactivity

human

status

RUO

Precio a consultar