Recombinant Human IGSF11

Este producto es parte de IGSF - immunoglobulin superfamily member
Recombinant Human IGSF11

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

Proteins IGSF11

proveedor

FineTest

reference

P5951

Tested Applications

Western Blot,ELISA

reactivity

status

RUO

clonality


Background

IGSF11 is a transmembrane adhesion molecule primarily expressed in the brain, where it is localized at excitatory synapses. It contains Ig-like domains that mediate homophilic and heterophilic interactions with other synaptic proteins, influencing synaptic organization and plasticity. IGSF11 is essential for the stabilization of AMPA receptors, which are critical for synaptic transmission and long-term potentiation (LTP). Dysregulation of IGSF11 has been implicated in neurodevelopmental disorders such as autism spectrum disorders (ASD) and schizophrenia. It also plays a role in tumor biology, where it modulates cancer cell adhesion and migration in certain cancers.

Características del producto

category

Proteins and Peptides


origin

Human


host

E.Coli


immunogen target

24-241


host

E.Coli


form

Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4


tested applications

Western Blot,ELISA


size 1

50μg


size 2

200μg


size 3

1mg


observerd MW

43.7 kDa


expression

Recombinant


purity

Greater than 95% by SDS-PAGE gel analyses


purification

IF2DI tag


buffer

Reconstitute with Sterile distilled water


storage

-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution


or code

IGSF11


availability

3-4 weeks


alias

CT119,VSIG3,BTIGSF,Igsf13,BT-IgSF,CXADRL1,V-set and immunoglobulin domain-containing protein ,Brain and testis-specific immunoglobulin superfamily protein


note

This product is for research use only.


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clonality

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