Name: Recombinant Human ACVR1B
Brand: FineTest
SKU: P0493
Availability: OnlineOnly

Background

ACVR1B, also known as ALK4, is a type I receptor primarily activated by activins, inhibins, and Nodal ligands. This receptor phosphorylates SMAD2/3 to propagate downstream signaling, which regulates cellular processes such as differentiation, proliferation, and embryonic patterning. ACVR1B is expressed in many tissues, particularly during early development. Mutations in ACVR1B have been associated with tumorigenesis and reproductive disorders due to its role in cell cycle regulation and tissue homeostasis.

Características del producto

origin

Human

host

E.Coli

immunogen target

24-126

host

E.Coli

form

Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4

tested applications

Western Blot, ELISA

size 1

50μg

size 2

200μg

size 3

1mg

observerd MW

32 KDa

expression

Recombinant

purity

Greater than 95% by SDS-PAGE gel analyses

purification

IF2DI tag

buffer

Reconstitute with Sterile distilled water

storage

-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution

or code

ACVR1B

availability

7 days

alias

ACTR-IB,ALK-4,Serine/threonine-protein kinase receptor R2 (SKR2)

uniprot id

https://www.uniprot.org/uniprotkb/P36896

note

This product is for research use only.

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anti- ACVR1B antibody

proveedor

FineTest

reference

FNab00129

Tested Applications

ELISA, WB, IHC

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Transmembrane serine/threonine kinase activin type-1 receptor forming an activin receptor complex with activin receptor ...

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