Recombinant Human ACVR1B
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935106861
info@markelab.com
Precio
Precio a consultar
Proteins ACVR1B
proveedor
FineTestreference
P0493Tested Applications
Western Blot, ELISAreactivity
status
RUOclonality
Background
ACVR1B, also known as ALK4, is a type I receptor primarily activated by activins, inhibins, and Nodal ligands. This receptor phosphorylates SMAD2/3 to propagate downstream signaling, which regulates cellular processes such as differentiation, proliferation, and embryonic patterning. ACVR1B is expressed in many tissues, particularly during early development. Mutations in ACVR1B have been associated with tumorigenesis and reproductive disorders due to its role in cell cycle regulation and tissue homeostasis.
Características del producto
category
Proteins and Peptides
origin
Human
host
E.Coli
immunogen target
24-126
host
E.Coli
form
Lyophilized from a 0.2um filtered solution in PBS with 5% trehalose, pH7.4
tested applications
Western Blot, ELISA
size 1
50μg
size 2
200μg
size 3
1mg
observerd MW
32 KDa
expression
Recombinant
purity
Greater than 95% by SDS-PAGE gel analyses
purification
IF2DI tag
buffer
Reconstitute with Sterile distilled water
storage
-20°C for 12 months as lyophilized;2-8°C for 1 month under sterile conditions after reconstitution
or code
ACVR1B
availability
7 days
alias
ACTR-IB,ALK-4,Serine/threonine-protein kinase receptor R2 (SKR2)
uniprot id
note
This product is for research use only.
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