Receptor-Type Tyrosine-Protein Phosphatase Delta (PTPRD) Antibody
351€ (100 µg)
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935106861
info@markelab.com
name
Receptor-Type Tyrosine-Protein Phosphatase Delta (PTPRD) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx375706
tested applications
ELISA, WB
Description
Receptor-Type Tyrosine-Protein Phosphatase Delta (PTPRD) Antibody is a Rabbit Polyclonal antibody against Receptor-Type Tyrosine-Protein Phosphatase Delta (PTPRD).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Receptor-Type Tyrosine-Protein Phosphatase Delta (PTPRD) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P23468 |
| Gene ID | 5789 |
| Alias | HPTP,PTPD,HPTPD,HPTPDELTA,RPTPDELTA,R-PTP-delta,Protein-tyrosine phosphatase delta,Receptor-type tyrosine-protein phosphatase delta |
| Background | Antibody anti-PTPRD |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
PTPRD is a receptor-like protein tyrosine phosphatase involved in cell-cell adhesion and neuronal development. It has extracellular immunoglobulin-like and fibronectin type III domains, a transmembrane segment, and two intracellular phosphatase domains. PTPRD plays a vital role in axon guidance, synapse formation, and neuronal survival. It interacts with various proteins to regulate key pathways in neuronal differentiation and connectivity. PTPRD is widely expressed in the brain and implicated in neurodevelopmental and psychiatric disorders, such as autism and ADHD. Additionally, PTPRD mutations or deletions are linked to tumor suppression in cancers like glioblastoma and lung cancer.
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