RAMP2 Antibody is a Rabbit Polyclonal antibody against RAMP2. The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.
Primary Antibodies
Polyclonal
Human, Mouse, Rat
Receptor Activity Modifying Protein 2 (RAMP2)
Rabbit
Unconjugated
Liquid
WB, IHC
Purified by affinity chromatography.
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
20 µl
50 µl
100 µl
200 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
RAMP2
No
Shipped within 5-10 working days.
RAMP2
NP_005845.2
This product is for research use only.
Transports the calcitonin gene-related peptide type 1 receptor(CALCRL) to the plasma membrane. Acts as a receptor for ad...
Precio a consultar
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