Rat Tachykinin Receptor 3 (TACR3) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for TACR3
proveedor
Abbexareference
abx517353Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Tachykinin Receptor 3 (TACR3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Tachykinin Receptor 3 (TACR3) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
TACR3, also known as NK3R, is a G protein-coupled receptor activated by neurokinin B (NKB), a neuropeptide involved in regulating multiple physiological processes. TACR3 primarily couples to Gq proteins, stimulating phospholipase C (PLC), increasing intracellular calcium, and modulating cell signaling. It is predominantly expressed in the central nervous system (CNS), particularly in regions involved in regulating reproductive functions and controlling circadian rhythms. TACR3 plays a critical role in regulating the hypothalamic-pituitary-gonadal axis, influencing reproductive hormone release, and modulating sexual behavior. In addition, it is involved in controlling mood and anxiety by regulating neurogenic inflammation. Dysregulation of TACR3 signaling has been linked to conditions such as infertility, mood disorders, and certain cancers. Targeting TACR3 with antagonists offers potential therapeutic benefits in treating disorders related to reproductive function, anxiety, and neurogenic inflammation.
Características del producto
category
ELISA Kits
immunogen target
Tachykinin Receptor 3 (TACR3)
reactivity
Rat
test range
0.312 ng/ml - 20 ng/ml
sensitivity
< 0.15 ng/ml
assay type
Competitive
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
TACR3,Neurokinin B receptor,neurokinin beta receptor,Nmkr,Tac3r,neuromedin K receptor,NK-3 receptor,SP-N receptor,HH11,NK-3R,NK3,NK3R,NKR,TAC3R,TAC3RL
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
TACR3
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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