Human TACR3 (Neuromedin-K receptor) ELISA Kit
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Name
Human TACR3 (Neuromedin-K receptor) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH1703
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.781-50ng/ml |
| Sensitivity | 0.469ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P29371 |
| Alias | TACR3,Neurokinin B receptor,neurokinin beta receptor,Nmkr,Tac3r,neuromedin K receptor,NK-3 receptor,SP-N receptor,HH11,NK-3R,NK3,NK3R,NKR,TAC3R,TAC3RL |
| Background | Elisa kits for TACR3 |
| Status | RUO |
Background
TACR3, also known as NK3R, is a G protein-coupled receptor activated by neurokinin B (NKB), a neuropeptide involved in regulating multiple physiological processes. TACR3 primarily couples to Gq proteins, stimulating phospholipase C (PLC), increasing intracellular calcium, and modulating cell signaling. It is predominantly expressed in the central nervous system (CNS), particularly in regions involved in regulating reproductive functions and controlling circadian rhythms. TACR3 plays a critical role in regulating the hypothalamic-pituitary-gonadal axis, influencing reproductive hormone release, and modulating sexual behavior. In addition, it is involved in controlling mood and anxiety by regulating neurogenic inflammation. Dysregulation of TACR3 signaling has been linked to conditions such as infertility, mood disorders, and certain cancers. Targeting TACR3 with antagonists offers potential therapeutic benefits in treating disorders related to reproductive function, anxiety, and neurogenic inflammation.
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