Rat Succinate Receptor 1 (SUCNR1) ELISA Kit
715€ (96 tests)
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935106861
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name
Rat Succinate Receptor 1 (SUCNR1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx392026
tested applications
ELISA
Description
Rat Succinate Receptor 1 (SUCNR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat SUCNR1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Succinate Receptor 1 (SUCNR1) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.07 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q6IYF9 |
| Gene ID | 408199 |
| Alias | SUCNR1,succinate receptor 1,GPR91,P2Y purinoceptor 1,SUCNR1,G protein-coupled receptor 91 |
| Background | Elisa kits for SUCNR1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
SUCNR1, also known as the succinate receptor, is a G protein-coupled receptor that is activated by succinate, an intermediate in the citric acid cycle and a key molecule in cellular metabolism. It primarily couples to Gi proteins, triggering intracellular signaling pathways that regulate vascular tone, inflammation, and metabolic processes. SUCNR1 is expressed in various tissues, including the kidney, vasculature, and immune cells. In the kidney, it plays a role in regulating blood pressure by modulating the renin-angiotensin system. In the vasculature, SUCNR1 is involved in regulating smooth muscle contraction and endothelial cell function, contributing to blood pressure homeostasis. Dysregulation of SUCNR1 has been linked to conditions such as hypertension, ischemia, and inflammation. SUCNR1 is also implicated in cancer progression, particularly in the context of tumor hypoxia. Targeting SUCNR1 with selective agonists or antagonists offers potential therapeutic strategies for managing metabolic diseases, cardiovascular disorders, and inflammation.
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