Rat Striatin (STRN) ELISA Kit

Este producto es parte de STRN - Striatin
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715€ (96 tests)

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935106861
info@markelab.com
name
Rat Striatin (STRN) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx547795
tested applications
ELISA

Description

Rat Striatin (STRN) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Striatin concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Striatin (STRN)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P70483
Alias
PPP2R6A,SG2NA,STRN1
Background
Elisa kits for STRN
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Striatin (STRN) is a scaffolding protein and a member of the striatin family, functioning as a critical component of the striatin-interacting phosphatase and kinase (STRIPAK) complex. STRN acts as an adaptor protein, facilitating protein-protein interactions and coordinating cellular signaling pathways, including protein phosphatase 2A (PP2A) activity and kinase signaling. It is highly expressed in the brain, heart, and endothelial tissues, where it participates in cellular processes such as vesicle trafficking, cytoskeletal organization, and signal transduction. STRN plays a significant role in neurodevelopment, neurotransmission, and endothelial cell function by regulating calcium-calmodulin-dependent pathways. Dysregulation of STRN is linked to neurological disorders, including neurodegenerative diseases, and cancers, where its involvement in PP2A activity affects tumor progression and cellular homeostasis. Knockdown studies reveal disrupted vesicular transport, impaired cell signaling, and defective cytoskeletal organization, underscoring its role in maintaining cell structure, signaling integrity, and physiological processes.

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